Z-VRPR-FMK trifluoroacetate salt ( )

Catalog No. M30776 CAS No.

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Z-VRPR-FMK trifluoroacetate salt
Note

Research use only, not for human use.
Brief Description

Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
Description

Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
Synonyms
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

CAS Number

--
Formula Weight

790.8
Molecular Formula

C31H49FN10O6.CF3CO2H
Purity

>98% (HPLC)
Solubility

water with gentle warming:1 mg/mL
SMILES

OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)CF
Chemical Name

1. Rebeaud et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 9 272 PMID:

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